The site provides reference information solely to familiarize yourself. Diagnosis and treatment of diseases must be under the supervision of a specialist. All drugs have contraindications. Consultation of a specialist is obligatory!
Characteristic of the drugDiazoline
(Mebirdroline) refers to the first generationAntihistamine drugs
. Despite the fact that antihistamine preparations of the second and even third generation have already appeared, diazoline did not lose its relevance today.
Antihistamine drugs are traditionally called drugs that are able to block the action of histamine. Histamine is a very active biological substance that is produced in the human body, both normally and under various pathological conditions. The most active histamine is allocated during allergic reactions in the respiratory organs, on the skin or in the eyes. At the same time, characteristic symptoms ariseAllergies
. Antihistamines prevent the development of allergic manifestations.
A distinctive feature of diazoline is its ability to penetrate very slightly through the hematorencephalic barrier, i.e. physiological obstacle between the blood system andHead Brain
. Due to this, after taking the drug, only a light soothing effect is observed, which allows the use of diazoline in the treatment of patients with violations of the CNS.
Diazoline reduces the swelling of the mucous membranes of the respiratory tract, relaxes the smooth muscles of the bronchi,Matties
, prevents excessive decreaseArterial pressure
, reduces the permeability of the walls of the vessels, eliminates redness of the skin.
Due to the fact that diazoline is able to influence some extent to other types of receptors, it has a contagon and painkillers.
The first effects of diazoline can be seen 15-30 minutes after taking the drug inside. The therapeutic maximum occurs after 3-4 hours, as a result of which 2-3 times of the drug during the day is allowed.
Diazoline passes biotransformation inliver
, and excreted from the body throughkidney
Forms of release
Diazoline is produced in two dosage forms - in tablets and dragees of 0.05 and 0.1 g. Tablets or dragee of 0.05 g belong to the children's dosage, and drugs are 0.1 g - to adult. The drug is produced in blister packs of 10 or 20 pieces, as well as in glass jars of 20 or 25 pieces.
Analogs of the drugIn the pharmacy network, it is often possible to meet not only the trading name of diazoline, but also its unmatched "names":
If there is a long time to be treated from any allergic disease, it is inevitably the need to choose an analogue of diazoline. In this case, it should be seen among the preparations of the first generation, because Antihistamines of older generation have other effects. Preparations likeDiMedrol.
, Diprazine (Pipolfen.
, Clelestine (Tueguil
According to its action, the most similar to diazolin. However, despite its similarity, they are not an absolutely identical replacement of diazoline, so assign analogs (actually, as well as the diazoline itself) can only a doctor.
Indications for use
Diazolin, as a rule, is used to treat or prevent the development of instant allergic reactions.
Diazoline is most effective at:one. Pollnosis
Allergic rhine and conjunctivitis;3. Krapivnice
Contact I.Atopic dermatitis
Skin reactions afterUkus
Bees, wasps, bumblebee, etc. Neyovy insects;8.
Angioedema edema (Sweet Qincke
And although the drug is transferred to patients is quite easily, the likelihood of side effects remains. In this regard, diazoline is practically not used in the treatment of chronic allergic diseases. Its main purpose - reliefSymptoms
acute allergic inflammation at the earliest stage.
ContraindicationsDiazoline is contraindicated to use people having the following diseases or conditions:
- Asthenodepressive syndrome;
- Epilepsy or tendency to convulsive syndrome;
- Organic diseases of the cardiovascular system and the violation of the heart rhythm;
- Athony (lethargy) of the intestine or bladder;
- Prostate hypertrophy;
- Clothing glaucoma.
Considering the irritant effect of the drug on the mucous membrane of the gastrointestinal tract, diazolines are not prescribed with ulcerative processes in the stomach and / or 12-risen intestine, inflammation of the intestinal walls.
It is prohibited to receive the drug to persons having intoleranceglucose
, as well as hypersensitivity to the main active ingredient (mebrohydrolin attack).
Diazoline is not prescribed pregnant and lactating women, children under 3 years old.
Diazolin is significantly enhanced by the effect of tranquilizing drugs, neuroleptics,Analgesic
, so while at the same time receiving these funds may appeardrowsiness
Weakness. Opposite effects can develop - excitation, euphoria, sleep disorder,headache
, violation of coordination of movements. The same states are when taking diazoline along with alcohol.
Diazoline with caution is prescribed to people whose type of activity is associated with an increased concentration of attention, as well as patients with violations of the CNS.Among other possible side effects should be called:
In the presence of diseases of the liver and / or kidney, the toxic effect of the drug may appear, which manifests itself in strengthening side effects. In this case, an urgent dose correction and multiplicity of diazoline reception per day is required, and in severe cases - complete cancellation of the drug.
Depending on the severity of symptoms, a single dose of diazoline is for adults 0.05-0.1 g to 3 times a day. The highest one-time dose for adults and children over 12 years is 0.3 g; daily - 0.6 g
How to take diazoline
Diazoline is recommended to take during or immediately after eating, not chewing. Pill or dragee should be powered by clean, non-carbonatedWater
The duration of the drug may vary from 3-5 to 7 days, depending on the nature of the disease and the reached therapeutic effect. In connection with the developing addiction, it is not prescribed for more than 7-10 days in a row. If necessary, a longer antiallergic treatment with diazolines is replaced by another antihistamine.
Diazoline during pregnancy
Due to the fact that diazoline penetrates through the placental barrier, it is not recommended to take it in the periodPregnancy
, especially in her first 12 weeks. In the future, it is allowed to receive diazoline with short courses - no longer than 3-5 days. And although diazoline is considered a relatively safe drug, for all time it is not covered by enough data for which it is possible to judge its absolute harmability for the fetus.
The same applies to the reception of diazoline whenlactation
- the drug can easily penetratebreast milk
Diazoline is prescribed in dragee or tablets of 0.05.One-time dose is:
- For children for 3-5 years - 0.05 g 1-2 times a day;
- For children 6-10 years old - 0.05 g 2-3 times a day;
- For children 10-12 years old - 0.05 g 3-4 times a day.
For children under 3 years old, the drug can prescribe a doctor when therapeutic effects will prevail over possible side effects. For up to 1 year, the drug is not prescribed.
The basis for the appointment of children's diazolin are the same pathologies as in adults - allergic dermatoses,conjunctivitis
, food and drug allergies, hay fever, allergic reactions after preventivevaccinations
In addition, diazoline is often used by doctors during treatmentARVI
. This is explained by the fact thatCostood
The child in the mucous membranes accumulates variousAllergens
Suulting can provoke a relapse of the disease. To prevent allergic reactions from the nasal ways, doctors prescribe prophylactic doses of diazoline. The onset of the positive effect of the drug serves as an indirect indication for the predisposition of the child to allergies and the need for a deeper survey.
Price of drug
Diazoline is considered a folk drug due to its publicly available and low cost. The average price for diazoline in pharmacies is 30-50 rubles, depending on the dosage of the active substance and the number of tablets (dragee) in the package.
Well, of course, the price of the drug strongly depends on the recognition of the manufacturer - the known trademark, under which the drug is released, the higher its value will be.
Reviews of application
About how diazoline acts, and its effectiveness in various allergic violations can be judged by the following reviews:Elena, St. Petersburg:
Diazoline prescribed us in dragee. Daughter - Allergicdermatitis
. A few days after taking the drug, noticed that the child had a paler's specks on the cheeks, and on the 5th day of treatment and were held at all. And before that, that only we did not try, nothing helped. After the pill, the daughter became more calm, not so much cleaned red places and began to sweep it easier. In general, we are very pleased that we had a good doctor who was able to finally cure a child with the help of such a simple and inexpensive drug. "Tatiana, Volgograd:
"For a long time I was allergic, a leggy leg was very very sculpted. To which there was such a reaction, I still did not understand. After my legs began to comb into blood, I decided that it was time to go to the doctor. She wrote to me Diazoline in tablets. I didn't really believe in success, and the price of the drug was suspiciously low. But oddly enough, the drug helped me almost immediately, the itch has decreased the next day, and after a couple of days it has completely stopped. Since then more than such "The scratches" never had. "Olga, New Pokrovka:
"I have allergic for many years. The doctor advised me to take a diazoline as ambulance, and now only I saves them. At the very first signs I start taking 1 tablet 2 times a day. Literally after 30 minutes, it becomes easier for me. I am very Satisfied with this drug, it really helps, and there is no drowsiness, as from other antihistamine means. "Ivan, Nizhny Novgorod:
"Doctors put the son diagnosis -diathesis
And prescribed children's diazolines. The medicine is familiar to me since my childhood (I myself suffered from food allergies) and was one hundred percent sure that it would help. So it was - diathesis left, and then we also translated the Son to hypoallergenicdiet
(Doctors said to not provoke the body) and no longer returned diathesis. Good medicine, what is called cheap and angry! But I would also add - and efficiently. "
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Diazoline is a drug that has an antihistamine effect. Can be used systemically.
Release form and composition
The drug is produced in two forms:
Active element - mebirdroline. Auxiliary ingredients: wax, sunflower oil, starch pattern.
The active substance significantly reduces the antismogenic effect of histamine, which refers to the smooth muscles of the lungs and intestines. Also has an action on the permeability of the vessels. The drug is endowed with anesthetic effect, but it manifests poorly.
Composite elements are quickly absorbed and begin to act in 20-25 minutes. The maximum result can be seen 1.5 hours after the reception. The effect is saved for 30-48 hours. From the body comes out with the help of kidneys.
Indications for use
The medicine is prescribed to prevent and treat allergic and seasonal rhinitis. It is also actively accepted with urban and allergies to medicines or food. Another readings include insect bites and skin rashes.
Diazoline is contraindicated to persons with:
With extreme caution, you can take in case of diseases of the liver and kidneys. In this case, the specialist must individually assign a treatment regimen and permissible dose. It is not recommended to take in the presence of heart problems.
From the head of the gastrointestinal tract: irritation of the mucous membrane, vomiting, nausea, heartburn.
From the nervous system: dizziness, weakness, drowsiness, slow perception of the surrounding.
To other side reactions include tremor, a feeling of dryness in the oral cavity, problems with urination, allergic to components, and breaking sleep.
The child may have excessive excitability, insomnia.
A single cases were recorded at which the swelling of the quinque and headache was manifested.
There may be cases of overdose, manifestations in the form: confusion of thinking, drowsiness, coordination problems, the oppression of the work of the CNS (may even lead to a coma). Children more often has a stimulating effect on the CNS. Also an overdose has the following symptoms: dry mouth, extended pupils, vomiting, nausea, pain in the area of the stomach.
When such reactions appear, you need to immediately refuse to receive medicine, provoke vomiting (you can take activated coal) and contact a specialist, which will appoint symptomatic treatment.
How to drink diazoline with allergies
The drug is intended for oral administration. The treatment diagram with allergies is as follows: from 12 years old can be given 150-200 mg no more than 2 times a day. The maximum allowable one-time dose for an adult - 300 mg, daily - 600 mg. A child from 5 to 12 years old can be given 50 mg 2-3 times a day. Children at the age of 1-5 give 50 mg no more than 2 times a day. Take the medicine after meals.
How to take diazoline at urban
An adult man needs to take 1 tablet three times a day. Children under 12 are prescribed 1 tablet 1-2 times a day.
The drug in the form of dragee is prescribed 100 ml three times per day to an adult person. Child can be given 50 ml 2 times a day.
How long can you take diazoline
Duration of reception of diazoline on average - 1 week. A more accurate term of treatment may assign a specialist with regard to the state of the patient.
How to take diazoline children
Diazoline for children is used according to the following scheme: to the bottle with granules you need to add 100 ml of drinking water, well stir for 2-3 minutes. Packaging is attached to a measuring cup, which will correctly determine the necessary dose. Tabs at the age of 2-3 years old can be given no more than 2.5 ml. A child from 4 to 6 years is prescribed 5 ml. Children at the age of 7-10 give 7.5 ml. Take the medicine you need 2-3 times a day after eating for 1 week. Before receiving, be sure to break the contents of the bottle.
How to drink diazoline pregnant
Women on the first and second trimester pregnancy is better to abandon the reception of Dizalon. In the third trimester, you can only be taken to appoint a specialist. Also worth refuse to use with breast feeding.
What is better: suprastin or diazoline
If you compare diazoline with a suprastine, then the first drug is a hypnotic and sedative action is much less pronounced.
After taking medication, it is necessary to abandon the driving and management of other mechanisms requiring increased concentration.
It is not necessary to take the drug along with alcohol, since the effect of the medication will be at times less.
The composition contains sucrose that it is worth considering people with the hereditary intolerance to fructose. Also with care to take with renal and liver failure.
Diazoline enhances the effect of sedative sleeping agents while using, as well as other drugs. Introducing the depressing effect on the central nervous system.
Shelf life - 3, 5 years from the date of production. It is necessary to store in a dark and dry place at a temperature not higher than 25 degrees.
Diazoline does not have direct analogues. A similar effect can be attributed to: Diprazine, Dimedrol, Supratine.
How much is diazoline
The drug can be purchased on any pharmacy, the doctor's recipe is not required. Cost of medication in tablets - 50 rubles., Dragee - 70-80 rubles.